abstract：:Worldwide, oocyte donors donate voluntarily or receive varying amounts of money for donation. This raises ethical questions regarding the appropriateness of financial compensation, and the possibility of undue inducement and exploitation of oocyte donors. Are these donors capable of making an independent, well-conside...

journal_title：Reproductive biomedicine online

authors： Bakker MR,Maas J,Bekker MH,Bredenoord AL,Fauser BC,Bos AM

更新日期：2017-08-01 00:00:00

abstract：:In nature, HCG is secreted by the implanting embryo from peri-implantation and onwards. In contrast, LH is mandatory for steroidogenesis and follicular development during the follicular phase, working in synergy with FSH. Moreover, LH is mandatory for the function of the corpus luteum. Although LH and HCG bind to the ...

journal_title：Reproductive biomedicine online

authors： Alsbjerg B,Elbaek HO,Laursen RJ,Povlsen BB,Haahr T,Yding Andersen C,Humaidan P

更新日期：2017-08-01 00:00:00

abstract：:Our understanding of the composition of the microbial communities that inhabit the human body, known as the 'microbiome', is aided by the development of non-culture-dependent DNA sequencing. It is increasingly apparent that the balance of microbial species greatly affects the health of the host. Disturbances in the co...

journal_title：Reproductive biomedicine online

authors： García-Velasco JA,Menabrito M,Catalán IB

更新日期：2017-07-01 00:00:00

abstract：:Recent studies reveal that polycystic ovary syndrome (PCOS) might be associated with cardiovascular autonomic dysfunction, but with inconsistent results. The aim of this meta-analysis was to study whether women with PCOS have cardiovascular autonomic dysfunction. PubMed, Web of Science, Cochrane Library and SCOPUS wer...

journal_title：Reproductive biomedicine online

authors： Gui J,Wang RH

更新日期：2017-07-01 00:00:00

abstract：:Single-embryo image assessment involves a high degree of inaccuracy because of the imprecise labelling of the transferred embryo images. In this study, we considered the entire transfer cycle to predict the implantation potential of embryos, and propose a novel algorithm based on a combination of local binary pattern ...

journal_title：Reproductive biomedicine online

authors： Tian Y,Wang W,Yin Y,Wang W,Duan F,Zhao S

更新日期：2017-05-01 00:00:00

abstract：:The evolution of preimplantation genetic screening (PGS) for aneuploidy to blastocyst biopsy and more sensitive 24-chromosome screening techniques has resulted in a new diagnostic category of PGS results: those classified as mosaic. This diagnosis presents significant challenges for clinicians in developing policies r...

journal_title：Reproductive biomedicine online

authors： Besser AG,Mounts EL

更新日期：2017-04-01 00:00:00

abstract：:The medical evaluation of recurrent pregnancy loss (RPL), the occurrence of two or more consecutive pregnancy losses prior to 20th week of gestation, is mainly focused on maternal factors. However, paternally expressed genes may also play a role in implantation and placenta quality. This study aimed to investigate the...

journal_title：Reproductive biomedicine online

authors： Amin-Beidokhti M,Mirfakhraie R,Zare-Karizi S,Karamoddin F

更新日期：2017-03-01 00:00:00

abstract：:Recurrent pregnancy loss (RPL) is defined by two or more failed pregnancies and accounts for only 1-5% of pregnancy failures. Treatment options for unexplained RPL (uRPL) are limited. Previous studies suggest a link between delayed implantation and pregnancy loss. Based on this, a timely signal for rescue of the corpu...

journal_title：Reproductive biomedicine online

authors： Fox C,Azores-Gococo D,Swart L,Holoch K,Savaris RF,Likes CE,Miller PB,Forstein DA,Lessey BA

更新日期：2017-03-01 00:00:00

abstract：:A cost analysis covering direct healthcare costs relating to IVF freeze-all policy was conducted. Normal- and high- responder patients treated with a freeze-all policy (n = 63) compared with fresh transfer IVF (n = 189) matched by age, body mass index, duration and cause of infertility, predictive factors for IVF (num...

journal_title：Reproductive biomedicine online

authors： Papaleo E,Pagliardini L,Vanni VS,Delprato D,Rubino P,Candiani M,Viganò P

更新日期：2017-01-01 00:00:00

abstract：:The aim of this study was to evaluate the use of biological serum markers, available routinely in most hospital clinical laboratories, in predicting successful outcomes of expectant management in women presenting with a missed miscarriage. This is a single centre observational prospective study over a 16-month period....

journal_title：Reproductive biomedicine online

authors： Memtsa M,Jauniaux E,Gulbis B,Nyrhinen NC,Jurkovic D

更新日期：2017-01-01 00:00:00

abstract：:Multifetal pregnancy reduction (MPR) is an accepted method of reducing complications of triplet pregnancies and higher-order multifetal pregnancies. Eighty-three pregnancies that underwent early (68 weeks) transvaginal MPR were compared with 125 pregnancies that underwent late (11-14 weeks) transabdominal MPR. Rates o...

journal_title：Reproductive biomedicine online

authors： Haas J,Barzilay E,Hourvitz A,Dor J,Lipitz S,Yinon Y,Shlomi M,Shulman A

更新日期：2016-11-01 00:00:00

abstract：:The aim of this study was to explore the achievement of parenthood 8 years after starting IVF, considering multiple pathways to parenthood during and after IVF treatment. Medical data on 6507 couples who began IVF between 2000 and 2002 were obtained from the databases of eight French IVF centres. Information on long-t...

journal_title：Reproductive biomedicine online

authors： Troude P,Santin G,Guibert J,Bouyer J,de La Rochebrochard E,DAIFI Group.

更新日期：2016-11-01 00:00:00

abstract：:The aim of this study was to assess the performance of first-trimester combined screening when replacing the chronological maternal age by Anti-Müllerian hormone (AMH) and antral follicle count (AFC)-derived ovarian ages, as the background risk in trisomy risk estimation. A total of 639 pregnant women who completed fi...

journal_title：Reproductive biomedicine online

authors： Grande M,Sabrià J,Borobio V,Mercadé I,Stergiotou I,Masoller N,Borrell A

更新日期：2016-10-01 00:00:00

abstract：:The aneuploidy rates in expanded blastocysts biopsied on days 5 and 6 development were assessed in women undergoing IVF followed by array comparative genomic hybridization. This study included 1171 expanded blastocysts from 465 patients. Among the 465 patients, 215 and 141 underwent embryo biopsy on day 5 and day 6 (4...

journal_title：Reproductive biomedicine online

authors： Piccolomini MM,Nicolielo M,Bonetti TC,Motta EL,Serafini PC,Alegretti JR

更新日期：2016-09-01 00:00:00

abstract：:The main adverse effect of IVF is the high multiple pregnancy rate resulting from the transfer of two or more embryos. The objective was to evaluate pregnancy rates in infertile women with a good prognosis who failed to conceive in a fresh elective single embryo transfer (eSET) and had a second cycle with elective dou...

journal_title：Reproductive biomedicine online

authors： Monteleone PA,Mirisola RJ,Gonçalves SP,Baracat EC,Serafini PC

更新日期：2016-08-01 00:00:00

abstract：:Cell-free seminal mRNA (cfs-mRNA) contains testis-specific transcripts from bilateral testes. This study determined the presence of DEAD box polypeptide 4 (DDX4) in cfs-mRNA to identify and characterize the incidence of Sertoli cell-only (SCO) syndrome in men with non-obstructive azoospermia (NOA). DDX4 cfs-mRNA was d...

journal_title：Reproductive biomedicine online

authors： Yu Q,Gu X,Shang X,Li H,Xiong C

更新日期：2016-08-01 00:00:00

abstract：:To assess the impact of endometriosis on obstetric outcomes and to determine whether the severity, location and surgical treatment of the disease before the pregnancy had an impact on the prevalence of these disorders, a monocentric, case-control study was performed. In total, 113 pregnancies obtained by assisted repr...

journal_title：Reproductive biomedicine online

authors： Jacques M,Freour T,Barriere P,Ploteau S

更新日期：2016-06-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) affects 5-10% of women of reproductive age and is the most common cause of anovulatory infertility. The treatment approaches to ovulation induction vary in efficacy, treatment duration and patient friendliness. The aim was to determine the most efficient, evidence-based method to achie...

journal_title：Reproductive biomedicine online

authors： Birch Petersen K,Pedersen NG,Pedersen AT,Lauritsen MP,la Cour Freiesleben N

更新日期：2016-06-01 00:00:00

abstract：:The M2 haplotype of the annexin A5 gene is a well-recognized predisposition factor for recurrent spontaneous abortion (RSA). A recent publication by Nagirnaja et al. (2015) in PLoS One discusses the risk role of the M2 haplotype for RSA in cases compared with controls of North European extraction and arrives at a nega...

journal_title：Reproductive biomedicine online

authors： Markoff A,Kurahashi H,Grandone E,Bogdanova N

更新日期：2016-05-01 00:00:00

abstract：:This retrospective cohort study observed the live birth rates as well as cumulative live birth rates in women with poor ovarian response (POR) undergoing IVF-embryo transfer treatment, stratified for age and cycle number. Four hundred and one patients with POR diagnosed according to the Bologna criteria were enrolled ...

journal_title：Reproductive biomedicine online

authors： Yang Y,Sun X,Cui L,Sheng Y,Tang R,Wei D,Qin Y,Li W,Chen ZJ

更新日期：2016-05-01 00:00:00

abstract：:This study investigates whether the timing of in-vivo and in-vitro maturation influences ooplasmic dysmaturity. This is a retrospective comparison of intracytoplasmic sperm injection (ICSI) cycles (index cycles) complicated by complete fertilization failure (CFF) to cycles with successful fertilization in the same pat...

journal_title：Reproductive biomedicine online

authors： Pereira N,Neri QV,Lekovich JP,Palermo GD,Rosenwaks Z

更新日期：2016-04-01 00:00:00

abstract：:Artificial oocyte activation using Ca(2+)ionophores or similar compounds is a widely applied technique in IVF laboratories. This is all the more interesting as most of the agents aiming for intracellular Ca(2+) increase do not result in physiological Ca(2+) oscillations but much rather cause a single Ca(2+) transient....

journal_title：Reproductive biomedicine online

authors： Ebner T,Montag M

更新日期：2016-03-01 00:00:00

abstract：:Spermatogenesis is a critical process for maintaining male fertility. Sustained spermatogonial stem cell self-renewal and differentiation ensures constant spermatogenesis, and several signalling pathways regulate this process. An increasing number of studies have suggested that the mammalian target of rapamycin (mTOR)...

journal_title：Reproductive biomedicine online

authors： Xu H,Shen L,Chen X,Ding Y,He J,Zhu J,Wang Y,Liu X

更新日期：2016-02-01 00:00:00

abstract：:Improved laboratory standards and better culture media have made extended culture to blastocyst stage a reality to identify embryos with maximum implantation potential. The strategy of extended culture has become more popular across the world at a time when regulatory bodies have emphasized the need to increase the up...

journal_title：Reproductive biomedicine online

authors： Maheshwari A,Hamilton M,Bhattacharya S

更新日期：2016-02-01 00:00:00

abstract：:In this retrospective study of 873 men enrolled for assisted reproduction techniques, relationships between sperm quality parameters, motile sperm organelle morphology examination (MSOME), DNA damage and live birth rate were evaluated. The presence of vacuoles in the sperm heads was detected by MSOME. Either chromatin...

journal_title：Reproductive biomedicine online

authors： Fortunato A,Boni R,Leo R,Nacchia G,Liguori F,Casale S,Bonassisa P,Tosti E

更新日期：2016-02-01 00:00:00

abstract：:A retrospective cohort study was performed with the followings aims: to evaluate the influence of paternal age on best embryo quality available for embryo transfer on the third day; biochemical pregnancy rate; miscarriage rate and ongoing pregnancy rate at 8 weeks' gestational age, after IVF or intracytoplasmic sperm ...

journal_title：Reproductive biomedicine online

authors： Meijerink AM,Ramos L,Fleischer K,Veltman JA,Hendriks JC,Braat DD

更新日期：2016-01-01 00:00:00

abstract：:The aim of this prospective, randomized clinical trial (RCT) was to evaluate whether the supplemental protein concentration in embryo transfer (ET) medium affects the clinical outcomes in IVF-ET. A total of 750 patients undergoing IVF-ET who met the inclusion criteria were randomly divided into three groups, according...

journal_title：Reproductive biomedicine online

authors： Huang J,Chen H,Lu X,Wang X,Xi H,Zhu C,Zhang F,Lv J,Ge H

更新日期：2016-01-01 00:00:00

abstract：:Massively parallel genome sequencing, also known as next-generation sequencing (NGS), is the latest approach for preimplantation genetic diagnosis. The purpose of this study was to determine whether NGS can accurately detect aneuploidy in human embryos. Low coverage genome sequencing was applied to trophectoderm biops...

journal_title：Reproductive biomedicine online

authors： Kung A,Munné S,Bankowski B,Coates A,Wells D

更新日期：2015-12-01 00:00:00

abstract：:Artificial oocyte activation (AOA) has been previously suggested as a means to overcome the problem of total fertilization failure, which affects about 1-3% of the intracytoplasmic sperm injection (ICSI) cycles. A preliminary study on the application of chemical AOA was conducted using A23187 Ca(2+) ionophore to impro...

journal_title：Reproductive biomedicine online

authors： Darwish E,Magdi Y

更新日期：2015-12-01 00:00:00

abstract：:Cross-border reproductive care (CBRC) is becoming increasingly common. Little is known about the motivations and information and support needs of people who cross borders to access surrogacy. This study aimed to explore: how those considering or undertaking extraterritorial surrogacy reach their decision; what other a...

journal_title：Reproductive biomedicine online

authors： Hammarberg K,Stafford-Bell M,Everingham S

更新日期：2015-11-01 00:00:00

abstract：:Fertility-preservation techniques for medical reasons are increasingly offered in national networks. Knowledge of the characteristics of counselled patients and techniques used are essential. The FertiPROTEKT network registry was analysed between 2007 and 2013, and included up to 85 university and non-university centr...

journal_title：Reproductive biomedicine online

authors： von Wolff M,Dittrich R,Liebenthron J,Nawroth F,Schüring AN,Bruckner T,Germeyer A

更新日期：2015-11-01 00:00:00

abstract：:Traceability of cells during IVF is a fundamental aspect of treatment, and involves witnessing protocols. Failure mode and effects analysis (FMEA) is a method of identifying real or potential breakdowns in processes, and allows strategies to mitigate risks to be developed. To examine the risks associated with witnessi...

journal_title：Reproductive biomedicine online

authors： Rienzi L,Bariani F,Dalla Zorza M,Romano S,Scarica C,Maggiulli R,Nanni Costa A,Ubaldi FM

更新日期：2015-10-01 00:00:00

abstract：:The embryologist presides over the fulfillment of a patient's treatment in the laboratory for IVF through use of assisted reproduction techniques, and is in a unique position to impart quality to the process. Although the technical skill of the embryologist is critical, the embryologist's contribution to quality is eq...

journal_title：Reproductive biomedicine online

authors： Go KJ

更新日期：2015-10-01 00:00:00

abstract：:This paper draws on the findings of the first survey of surrogacy arrangements in Human Fertilisation and Embryology Authority (HFEA) licensed fertility clinics since 1998. Given the complex social, ethical and legal issues involved, surrogacy continues to raise debate worldwide and fuel calls for increased domestic p...

journal_title：Reproductive biomedicine online

authors： Norton W,Crawshaw M,Hudson N,Culley L,Law C

更新日期：2015-09-01 00:00:00

abstract：:A small number of studies from the USA and Europe have provided some data on the profile and characteristics of women who have undergone oocyte cryopreservation for what has been termed elective, social or non-medical reasons; however, little is known in a UK context about which women are undergoing oocyte cryopreserv...

journal_title：Reproductive biomedicine online

authors： Baldwin K,Culley L,Hudson N,Mitchell H,Lavery S

更新日期：2015-08-01 00:00:00

abstract：:Time-lapse technique provides opportunities to observe the dynamic process of human early development. Previous studies have suggested several abnormal division patterns were associated with decreased developmental potential, but no systematic results are currently available. In this study, seven abnormal division pat...

journal_title：Reproductive biomedicine online

authors： Yang ST,Shi JX,Gong F,Zhang SP,Lu CF,Tan K,Leng LZ,Hao M,He H,Gu YF,Lu GX,Lin G

更新日期：2015-06-01 00:00:00

abstract：:In 2012, the Czech Republic established the women's age limit for access to assisted reproduction techniques at age 49 years. In this paper, the acceptability of this age limit from the children's perspective in the Czech Republic is assessed. Although the necessity of balancing the interests of parents and children i...

journal_title：Reproductive biomedicine online

authors： Kocourková J,Konečná H,Burcin B,Kučera T

更新日期：2015-05-01 00:00:00

abstract：:To investigate the development of follicles and incidence of apoptosis in vitrified cultured mouse ovaries in the presence and absence of Kit ligand, 1-week-old mouse ovaries were cultured in the presence or absence of Kit ligand for 7 days. Development and function of ovarian follicles was evaluated by histology and ...

journal_title：Reproductive biomedicine online

authors： Abdi S,Salehnia M,Hosseinkhani S

更新日期：2015-05-01 00:00:00

abstract：:Myomectomy is the most frequent reproductive surgery to preserve, improve fertility, or both. The present study was designed to assess the safety and efficacy of minilaparotomy for myomectomy through a systematic review of randomized and non-randomized controlled trials with a meta-analysis. All available studies comp...

journal_title：Reproductive biomedicine online

authors： Palomba S,Fornaciari E,Falbo A,La Sala GB

更新日期：2015-05-01 00:00:00

abstract：:Endometriosis is a complex disease that is influenced by genetic and environmental factors. In endometriosis, WNT4 plays a likely role owing to its biological functions. In this study, the TaqMan allelic discrimination technique was used to investigate the relationship between endometriosis and four single nucleotide ...

journal_title：Reproductive biomedicine online

authors： Wu Z,Yuan M,Li Y,Fu F,Ma W,Li H,Wang W,Wang S

更新日期：2015-04-01 00:00:00